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The summed activity accounts for the neuronal ensemble pattern of the SCN, indicating that circadian waveform of electrical activity is a composed tissue property. The recorded single unit activity pattern was used to simulate the responsiveness of SCN neurons to different photoperiods. We inferred predictions on changes in peak width, amplitude, and peak time in the multiunit activity pattern and confirmed these predictions with hypothalamic slices from animals that had been kept in a short or long photoperiod. We propose that the animals' ability to code for day length derives from plasticity in the neuronal network of oscillating SCN neurons.<\/jats:p>","DOI":"10.1073\/pnas.2436298100","type":"journal-article","created":{"date-parts":[[2003,12,23]],"date-time":"2003-12-23T17:58:11Z","timestamp":1072202291000},"page":"15994-15999","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":185,"title":["Heterogeneity of rhythmic suprachiasmatic nucleus neurons: Implications for circadian waveform and photoperiodic encoding"],"prefix":"10.1073","volume":"100","author":[{"given":"Jeroen","family":"Schaap","sequence":"first","affiliation":[{"name":"Departments of Neurophysiology and Medical Statistics, Leiden University Medical Center, Wassenaarseweg 62, Leiden, The Netherlands; and Department of Physiology and Neurobiology, E\u00f6tv\u00f6s Lor\u00e1nd University, H-1117 Budapest, Hungary"}]},{"given":"Henk","family":"Albus","sequence":"additional","affiliation":[{"name":"Departments of Neurophysiology and Medical Statistics, Leiden University Medical Center, Wassenaarseweg 62, Leiden, The Netherlands; and Department of Physiology and Neurobiology, E\u00f6tv\u00f6s Lor\u00e1nd University, H-1117 Budapest, Hungary"}]},{"given":"Henk Tjebbe","family":"vanderLeest","sequence":"additional","affiliation":[{"name":"Departments of Neurophysiology and Medical Statistics, Leiden University Medical Center, Wassenaarseweg 62, Leiden, The Netherlands; and Department of Physiology and Neurobiology, E\u00f6tv\u00f6s Lor\u00e1nd University, H-1117 Budapest, Hungary"}]},{"given":"Paul H. 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