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Lower pH is required for prepore-to-pore conversion in the presence of the receptor, indicating that this interaction regulates pH-dependent pore formation. We present an example of a receptor negatively regulating pH-dependent membrane insertion.<\/jats:p>","DOI":"10.1073\/pnas.0405405101","type":"journal-article","created":{"date-parts":[[2004,8,23]],"date-time":"2004-08-23T20:16:39Z","timestamp":1093292199000},"page":"13147-13151","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":199,"title":["Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation"],"prefix":"10.1073","volume":"101","author":[{"given":"D. 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