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The most important factors contributing to the genetic variability of\n                    <jats:italic>C. albicans<\/jats:italic>\n                    are individual patient and gender. Our data manifest that the population size of the parasite is relatively small within each patient, although larger in women than in men, and that, at least for the patients involved in the study, the transmission rate of\n                    <jats:italic>C. albicans<\/jats:italic>\n                    between human adults is very low. Most important is the inference that the prevailing mode of reproduction of\n                    <jats:italic>C. albicans<\/jats:italic>\n                    in natural populations is clonal, so that sexual reproduction is extremely rare, if it occurs at all.\n                  <\/jats:p>","DOI":"10.1073\/pnas.0511328103","type":"journal-article","created":{"date-parts":[[2006,2,24]],"date-time":"2006-02-24T20:34:46Z","timestamp":1140813286000},"page":"3663-3668","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":44,"title":["Clonal population structure and genetic diversity of\n                    <i>Candida albicans<\/i>\n                    in AIDS patients from Abidjan (C\u00f4te d\u2019Ivoire)"],"prefix":"10.1073","volume":"103","author":[{"given":"Fran\u00e7ois","family":"N\u00e9bavi","sequence":"first","affiliation":[{"name":"*Laboratoire de Parasitologie et Mycologie M\u00e9dicale, EA 2413, Facult\u00e9 de Pharmacie, 34060 Montpellier Cedex 1, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco J.","family":"Ayala","sequence":"additional","affiliation":[{"name":"Department of Ecology and Evolutionary Biology, University of California, Irvine, CA 92697"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Renaud","sequence":"additional","affiliation":[{"name":"G\u00e9n\u00e9tique et Evolution des Maladies Infectieuses, Equipe Evolution des Syst\u00e8mes Symbiotiques, Unit\u00e9 Mixte de Recherche 2724, Institute de Recherche pour le D\u00e9veloppement, Centre National de la Recherche Scientifique, BP 64501, 34394 Montpellier Cedex 5, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Bertout","sequence":"additional","affiliation":[{"name":"*Laboratoire de Parasitologie et Mycologie M\u00e9dicale, EA 2413, Facult\u00e9 de Pharmacie, 34060 Montpellier Cedex 1, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serge","family":"Eholi\u00e9","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire de Treichville, 01 BP V 3 Abidjan, C\u00f4te d\u2019Ivoire;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kon\u00e9","family":"Moussa","sequence":"additional","affiliation":[{"name":"Laboratoire de Parasitologie Mycologie, Institut Pasteur de C\u00f4te d\u2019Ivoire, BP V 116 Abidjan, C\u00f4te d\u2019Ivoire; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mich\u00e8le","family":"Malli\u00e9","sequence":"additional","affiliation":[{"name":"*Laboratoire de Parasitologie et Mycologie M\u00e9dicale, EA 2413, Facult\u00e9 de Pharmacie, 34060 Montpellier Cedex 1, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"de Mee\u00fbs","sequence":"additional","affiliation":[{"name":"G\u00e9n\u00e9tique et Evolution des Maladies Infectieuses, Equipe Evolution des Syst\u00e8mes Symbiotiques, Unit\u00e9 Mixte de Recherche 2724, Institute de Recherche pour le D\u00e9veloppement, Centre National de la Recherche Scientifique, BP 64501, 34394 Montpellier Cedex 5, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2006,2,24]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.289.5477.307"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrg948"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.54.1.463"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2004.06.002"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/167.5.1247"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0732-8893(99)00035-8"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-004-1820-x"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.12.5899-5903.2004"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.phyto.34.1.457"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(97)00180-X"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.genet.33.1.449"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.12.1.126"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.7.2414"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-4922(02)02357-7"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tree.2005.01.001"},{"key":"e_1_3_3_16_2","author":"de Mee\u00fbs T.","year":"2006","unstructured":"T. de Mee\u00fbs, L. 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