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F-spondin, which is present in the stream, may act as ligand for ApoER2 and VLDLR. In mice lacking either both receptors or Dab1 chain formation is severely compromised, and as a consequence the rostral migratory stream is virtually absent and neuroblasts accumulate in the subventricular zone. The mutant animals exhibit severe neuroanatomical defects in the subventricular zone and in the olfactory bulb. These data demonstrate a cell-autonomous function of ApoER2, and most likely VLDLR and Dab1, in postnatal migration of neuroblasts in the forebrain, which is suggested to depend on ligands other than Reelin.<\/jats:p>","DOI":"10.1073\/pnas.0611391104","type":"journal-article","created":{"date-parts":[[2007,5,9]],"date-time":"2007-05-09T20:53:32Z","timestamp":1178744012000},"page":"8508-8513","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":59,"title":["ApoER2\/VLDL receptor and Dab1 in the rostral migratory stream function in postnatal neuronal migration independently of Reelin"],"prefix":"10.1073","volume":"104","author":[{"given":"Nuno","family":"Andrade","sequence":"first","affiliation":[{"name":"*Max F. Perutz Laboratories, University Departments at the Vienna Biocenter, Department of Medical Biochemistry, Medical University of Vienna, A-1030 Vienna, Austria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vukoslav","family":"Komnenovic","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biotechnology, Austrian Academy of Sciences, 1030 Vienna, Austria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia M.","family":"Blake","sequence":"additional","affiliation":[{"name":"*Max F. 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