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Moreover, we show that to protect, recall CD8\n                    <jats:sup>+<\/jats:sup>\n                    T cells directly kill targets in the lymph node draining the primary site of infection thus curbing systemic viral spread. Therefore, our work provides the basis for a model where lymph nodes are not just organs where lymphocytes become activated and proliferate but also the sites where a major fight against virus spread takes place.\n                  <\/jats:p>","DOI":"10.1073\/pnas.0701822104","type":"journal-article","created":{"date-parts":[[2007,6,19]],"date-time":"2007-06-19T23:09:05Z","timestamp":1182294545000},"page":"10992-10997","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":52,"title":["Memory CD8\n                    <sup>+<\/sup>\n                    T cells are gatekeepers of the lymph node draining the site of viral infection"],"prefix":"10.1073","volume":"104","author":[{"given":"Ren-Huan","family":"Xu","sequence":"first","affiliation":[{"name":"*Program of Viral Pathogenesis and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Fang","sequence":"additional","affiliation":[{"name":"*Program of Viral 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