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Correlated activity fluctuations of default mode network regions are identified during (\n                    <jats:italic>i<\/jats:italic>\n                    ) eyes-closed spontaneous rest, (\n                    <jats:italic>ii<\/jats:italic>\n                    ) activation by moral dilemma, and (\n                    <jats:italic>iii<\/jats:italic>\n                    ) deactivation by Stroop task performance. Across these imaging states, striking uniformity is shown in the basic anatomy of the default mode network, but with both tasks clearly and differentially modulating this activity compared with spontaneous fluctuations of the network at rest. Against rest, moral dilemma is further shown to evoke regionally specific activity increases of hypothesized functional relevance. Mapping spontaneous and task-related brain activity will help to constrain the meaning of the default mode network. These findings are discussed in relation to recent debate on the topic of default modes of brain function.\n                  <\/jats:p>","DOI":"10.1073\/pnas.0711791105","type":"journal-article","created":{"date-parts":[[2008,7,9]],"date-time":"2008-07-09T21:09:33Z","timestamp":1215637773000},"page":"9781-9786","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":323,"title":["Consistency and functional specialization in the default mode brain network"],"prefix":"10.1073","volume":"105","author":[{"given":"Ben J.","family":"Harrison","sequence":"first","affiliation":[{"name":"*Institut d'Alta Tecnologia-Parc de Recerca Biom\u00e8dica de Barcelona, CRC Corporaci\u00f3 Sanit\u00e0ria, 08003 Barcelona, Spain;"},{"name":"Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Melbourne 3053, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesus","family":"Pujol","sequence":"additional","affiliation":[{"name":"*Institut d'Alta Tecnologia-Parc de Recerca Biom\u00e8dica de Barcelona, CRC Corporaci\u00f3 Sanit\u00e0ria, 08003 Barcelona, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"L\u00f3pez-Sol\u00e0","sequence":"additional","affiliation":[{"name":"*Institut d'Alta Tecnologia-Parc de Recerca Biom\u00e8dica de Barcelona, CRC Corporaci\u00f3 Sanit\u00e0ria, 08003 Barcelona, Spain;"},{"name":"Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Hern\u00e1ndez-Ribas","sequence":"additional","affiliation":[{"name":"*Institut d'Alta Tecnologia-Parc de Recerca Biom\u00e8dica de Barcelona, CRC Corporaci\u00f3 Sanit\u00e0ria, 08003 Barcelona, Spain;"},{"name":"Department of Psychiatry, Bellvitge University Hospital, 08907 Barcelona, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Deus","sequence":"additional","affiliation":[{"name":"*Institut d'Alta Tecnologia-Parc de Recerca Biom\u00e8dica de Barcelona, CRC Corporaci\u00f3 Sanit\u00e0ria, 08003 Barcelona, Spain;"},{"name":"Department of Clinical and Health Psychology, Autonomous University of Barcelona, 08193 Barcelona, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hector","family":"Ortiz","sequence":"additional","affiliation":[{"name":"*Institut d'Alta Tecnologia-Parc de Recerca Biom\u00e8dica de Barcelona, CRC Corporaci\u00f3 Sanit\u00e0ria, 08003 Barcelona, Spain;"},{"name":"**Department of Electronic Engineering, Technical University of Catalonia, 08034 Barcelona, Spain; 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