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In this study, we demonstrate the specific binding of antibody-coupled CNTs to tumor cells\n                    <jats:italic>in vitro<\/jats:italic>\n                    , followed by their highly specific ablation with NIR light. Biotinylated polar lipids were used to prepare stable, biocompatible, noncytotoxic CNT dispersions that were then attached to one of two different neutralite avidin-derivatized mAbs directed against either human CD22 or CD25. CD22\n                    <jats:sup>+<\/jats:sup>\n                    CD25\n                    <jats:sup>\u2212<\/jats:sup>\n                    Daudi cells bound only CNTs coupled to the anti-CD22 mAb; CD22\n                    <jats:sup>\u2212<\/jats:sup>\n                    CD25\n                    <jats:sup>+<\/jats:sup>\n                    activated peripheral blood mononuclear cells bound only to the CNTs coupled to the anti-CD25 mAb. Most importantly, only the specifically targeted cells were killed after exposure to NIR light.\n                  <\/jats:p>","DOI":"10.1073\/pnas.0803557105","type":"journal-article","created":{"date-parts":[[2008,6,16]],"date-time":"2008-06-16T21:11:20Z","timestamp":1213650680000},"page":"8697-8702","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":330,"title":["Thermal ablation of tumor cells with antibody-functionalized single-walled carbon nanotubes"],"prefix":"10.1073","volume":"105","author":[{"given":"Pavitra","family":"Chakravarty","sequence":"first","affiliation":[{"name":"*The Cancer Immunobiology Center, University of Texas Southwestern Medical Center, Dallas, TX 75390;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radu","family":"Marches","sequence":"additional","affiliation":[{"name":"*The Cancer Immunobiology Center, University of Texas Southwestern Medical Center, Dallas, TX 75390;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil S.","family":"Zimmerman","sequence":"additional","affiliation":[{"name":"Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Austin D.-E.","family":"Swafford","sequence":"additional","affiliation":[{"name":"Departments of \u00a7Molecular and Cell Biology and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pooja","family":"Bajaj","sequence":"additional","affiliation":[{"name":"Chemistry, University of Texas at Dallas, Richardson, TX 75080"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inga H.","family":"Musselman","sequence":"additional","affiliation":[{"name":"The Alan G. 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MacDiarmid NanoTech Institute and"},{"name":"Departments of \u00a7Molecular and Cell Biology and"},{"name":"Chemistry, University of Texas at Dallas, Richardson, TX 75080"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen S.","family":"Vitetta","sequence":"additional","affiliation":[{"name":"*The Cancer Immunobiology Center, University of Texas Southwestern Medical Center, Dallas, TX 75390;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2008,6,24]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrc706"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1204000"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.54.101601.152442"},{"key":"e_1_3_3_4_2","first-page":"1490","article-title":"Approval summary: Gemtuzumab ozogamicin in relapsed acute myeloid leukemia","volume":"7","author":"Bross PF","year":"2001","unstructured":"PF Bross, et al., Approval summary: Gemtuzumab ozogamicin in relapsed acute myeloid leukemia. 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