{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:02:34Z","timestamp":1793059354265,"version":"4.5.0"},"reference-count":50,"publisher":"National Academy of Sciences","issue":"13","content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[2009,3,31]]},"abstract":"<jats:p>\n                    Flowering plants often prevent selfing through mechanisms of self-incompatibility (S.I.). The loss of S.I. has occurred many times independently, because it provides short-term advantages in situations where pollinators or mates are rare. The genus\n                    <jats:italic>Capsella<\/jats:italic>\n                    , which is closely related to\n                    <jats:italic>Arabidopsis<\/jats:italic>\n                    , contains a pair of closely related diploid species, the self-incompatible\n                    <jats:italic>Capsella grandiflora<\/jats:italic>\n                    and the self-compatible\n                    <jats:italic>Capsella rubella<\/jats:italic>\n                    . To elucidate the transition to selfing and its relationship to speciation of\n                    <jats:italic>C. rubella<\/jats:italic>\n                    , we have made use of comparative sequence information. Our analyses indicate that\n                    <jats:italic>C. rubella<\/jats:italic>\n                    separated from\n                    <jats:italic>C. grandiflora<\/jats:italic>\n                    recently (\u224830,000\u201350,000 years ago) and that breakdown of S.I. occurred at approximately the same time. Contrasting the nucleotide diversity patterns of the 2 species, we found that\n                    <jats:italic>C. rubella<\/jats:italic>\n                    has only 1 or 2 alleles at most loci, suggesting that it originated through an extreme population bottleneck. Our data are consistent with diploid speciation by a single, selfing individual, most likely living in Greece. The new species subsequently colonized the Mediterranean by Northern and Southern routes, at a time that also saw the spread of agriculture. The presence of phenotypic diversity within modern\n                    <jats:italic>C. rubella<\/jats:italic>\n                    suggests that this species will be an interesting model to understand divergence and adaptation, starting from very limited standing genetic variation.\n                  <\/jats:p>","DOI":"10.1073\/pnas.0808012106","type":"journal-article","created":{"date-parts":[[2009,3,23]],"date-time":"2009-03-23T21:30:41Z","timestamp":1237843841000},"page":"5246-5251","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":220,"title":["Recent speciation of\n                    <i>Capsella rubella<\/i>\n                    from\n                    <i>Capsella grandiflora<\/i>\n                    , associated with loss of self-incompatibility and an extreme bottleneck"],"prefix":"10.1073","volume":"106","author":[{"given":"Ya-Long","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 T\u00fcbingen, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesper S.","family":"Bechsgaard","sequence":"additional","affiliation":[{"name":"Ecology and Genetics, Institute of Biological Sciences, University of Aarhus, 8000 Aarhus C, Denmark;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Slotte","sequence":"additional","affiliation":[{"name":"Program in Evolutionary Functional Genomics, Uppsala University, 75326 Uppsala, Sweden; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Neuffer","sequence":"additional","affiliation":[{"name":"Department of Systematic Botany, University of Osnabr\u00fcck, 49076 Osnabr\u00fcck, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Lascoux","sequence":"additional","affiliation":[{"name":"Program in Evolutionary Functional Genomics, Uppsala University, 75326 Uppsala, Sweden; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Detlef","family":"Weigel","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 T\u00fcbingen, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikkel H.","family":"Schierup","sequence":"additional","affiliation":[{"name":"Ecology and Genetics, Institute of Biological Sciences, University of Aarhus, 8000 Aarhus C, Denmark;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2009,3,31]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrg776"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.231386798"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1086\/523362"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2008.01.002"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/genetics\/24.4.538"},{"key":"e_1_3_3_6_2","first-page":"347","article-title":"Self-compatibility and establishment after \u201clong-distance\u201d dispersal","volume":"9","author":"Baker H","year":"1955","unstructured":"H Baker, Self-compatibility and establishment after \u201clong-distance\u201d dispersal. 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