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We report that the patients showed enhanced visual awareness when tasks were performed under preferred music conditions relative to when tasks were performed either with unpreferred music or in silence. These results were also replicated when positive affect was induced before neglect was tested. Functional MRI data showed enhanced activity in the orbitofrontal cortex and the cingulate gyrus associated with emotional responses when tasks were performed with preferred music relative to unpreferred music. Improved awareness of contralesional (left) targets with preferred music was also associated with a strong functional coupling between emotional areas and attentional brain regions in spared areas of the parietal cortex and early visual areas of the right hemisphere. These findings suggest that positive affect, generated by preferred music, can decrease visual neglect by increasing attentional resources. We discuss the possible roles of arousal and mood in generating these effects.<\/jats:p>","DOI":"10.1073\/pnas.0811681106","type":"journal-article","created":{"date-parts":[[2009,3,23]],"date-time":"2009-03-23T21:30:41Z","timestamp":1237843841000},"page":"6011-6016","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":115,"title":["Pleasant music overcomes the loss of awareness in patients with visual neglect"],"prefix":"10.1073","volume":"106","author":[{"given":"David","family":"Soto","sequence":"first","affiliation":[{"name":"Division of Neuroscience and Mental Health, Faculty of Medicine, Charing Cross Hospital, Imperial College London, St. Dunstan's Road, London W6 8RP, United Kingdom;"},{"name":"Behavioural Brain Sciences Centre, School of Psychology, University of Birmingham, Birmingham B15 2TT, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda J.","family":"Funes","sequence":"additional","affiliation":[{"name":"Departamento de Psicolog\u00eda Experimental y Fisiolog\u00eda del Comportamiento, Facultad de Psicolog\u00eda, Campus de Cartuja, Universidad de Granada, Granada 18701, Spain; 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