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The S domain adopts a jelly-roll fold commonly observed in small RNA viruses. The P1 and P2 domains both adopt \u03b2-barrel folds. Each domain possesses a potential polysaccharide-binding site that may function in cell-receptor binding. Sugar binding to P1 at the capsid protein interface may lead to capsid disassembly and cell entry. Structural modeling indicates that native T = 3 capsid contains flat dimers, with less curvature than those of T = 1 VLP. 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