{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T15:38:00Z","timestamp":1781105880633,"version":"3.54.1"},"reference-count":20,"publisher":"National Academy of Sciences","issue":"21","content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[2012,5,22]]},"DOI":"10.1073\/pnas.1205457109","type":"journal-article","created":{"date-parts":[[2012,5,17]],"date-time":"2012-05-17T09:44:38Z","timestamp":1337247878000},"page":"7955-7956","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":11,"title":["Tumor suppressor p53 (\n                    <i>TP53<\/i>\n                    ) at the crossroads of the exposome and the cancer genome"],"prefix":"10.1073","volume":"109","author":[{"given":"Aaron J.","family":"Schetter","sequence":"first","affiliation":[{"name":"Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Curtis C.","family":"Harris","sequence":"additional","affiliation":[{"name":"Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2012,5,18]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/342705a0"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1905840"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1208130"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature10166"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1119920109"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a001008"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/350427a0"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/350429a0"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.22.10124"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.2554494"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a001107"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1566048"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.10.031"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.11.2309"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-05-0456"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1192603"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(82)90078-9"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200007133430210"},{"key":"e_1_3_3_19_2","first-page":"2","article-title":"The predictive capacity of personal genome sequencing","volume":"2012","author":"Roberts NJ","year":"2012","unstructured":"NJ Roberts, et al., The predictive capacity of personal genome sequencing. Sci Transl Med 2012, 2 (2012).","journal-title":"Sci Transl Med"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature09792"}],"container-title":["Proceedings of the National Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pnas.org\/doi\/pdf\/10.1073\/pnas.1205457109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,12]],"date-time":"2022-04-12T21:06:47Z","timestamp":1649797607000},"score":1,"resource":{"primary":{"URL":"https:\/\/pnas.org\/doi\/full\/10.1073\/pnas.1205457109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,18]]},"references-count":20,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2012,5,22]]}},"alternative-id":["10.1073\/pnas.1205457109"],"URL":"https:\/\/doi.org\/10.1073\/pnas.1205457109","relation":{},"ISSN":["0027-8424","1091-6490"],"issn-type":[{"value":"0027-8424","type":"print"},{"value":"1091-6490","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,18]]},"assertion":[{"value":"2012-05-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}