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After rabies injections into area 46, many neurons in the restricted region of the posterior interpositus nucleus (PIN) were labeled disynaptically via the thalamus, whereas no neuron labeling was found in the anterior interpositus nucleus (AIN). The distribution of the labeled neurons was dorsoventrally different from that of PIN neurons labeled from the M1. This defines an anatomical substrate for the contribution of medial cerebellar output to cognitive functions. Like the dentate nucleus, the PIN has dual motor and cognitive channels, whereas the AIN has a motor channel only.<\/jats:p>","DOI":"10.1073\/pnas.1211168109","type":"journal-article","created":{"date-parts":[[2012,10,30]],"date-time":"2012-10-30T01:46:22Z","timestamp":1351561582000},"page":"18980-18984","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":34,"title":["Anatomical evidence for the involvement of medial cerebellar output from the interpositus nuclei in cognitive functions"],"prefix":"10.1073","volume":"109","author":[{"given":"Xiaofeng","family":"Lu","sequence":"first","affiliation":[{"name":"Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Tokyo 183-8526, Japan;"},{"name":"Brain Sciences Center, Veterans Administration Medical Center, Minneapolis, MN 55417;"},{"name":"Department of Neurology, School of Medicine, University of Minnesota, Minneapolis, MN 55414;"},{"name":"Department of Neurophysiology, School of Medicine, Juntendo University, Tokyo 113-8421, Japan; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigehiro","family":"Miyachi","sequence":"additional","affiliation":[{"name":"Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Tokyo 183-8526, Japan;"},{"name":"Cognitive Neuroscience Section and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Takada","sequence":"additional","affiliation":[{"name":"Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Tokyo 183-8526, Japan;"},{"name":"Systems Neuroscience Section, Primate Research Institute, Kyoto University, Inuyama, Aichi 484-8506, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2012,10,29]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(93)90072-T"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-02-00700.2001"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1037\/0735-7044.106.6.879"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1101\/lm.3.6.545"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0601150103"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1101\/lm.1178309"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1037\/a0014263"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0270(00)00296-X"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.2002.01994.x"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1223-04.2004"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4186-04.2005"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2007.05482.x"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/382629a0"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhh093"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(74)90389-8"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.01011.2005"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2453"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.291.5502.312"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.17.8122"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0173(99)00040-5"},{"key":"e_1_3_3_21_2","first-page":"299","article-title":"Organization of the thalamo-cortical connexions to the frontal lobe in the rhesus monkey","volume":"29","author":"Kievit J","year":"1977","unstructured":"J Kievit, HG Kuypers, Organization of the thalamo-cortical connexions to the frontal lobe in the rhesus monkey. 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