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Previous studies found that mutations in the ZIP13 gene,\n                    <jats:italic>SLC39A13<\/jats:italic>\n                    , cause the spondylocheiro dysplastic form of Ehlers\u2013Danlos syndrome (SCD-EDS) and speculated that ZIP13 exports zinc from the early secretory pathway and that zinc overload in the endoplasmic reticulum causes SCD-EDS. In contrast, our study suggests that SCD-EDS results from zinc deficiency in the endoplasmic reticulum resulting from zinc trapping in vesicular stores.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1211775110","type":"journal-article","created":{"date-parts":[[2012,12,4]],"date-time":"2012-12-04T10:41:27Z","timestamp":1354617687000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":109,"title":["Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers\u2013Danlos syndrome"],"prefix":"10.1073","volume":"109","author":[{"given":"Jeeyon","family":"Jeong","sequence":"first","affiliation":[{"name":"Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI 53706;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel M.","family":"Walker","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI 53706;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fudi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI 53706;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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