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Pharmacological manipulations and genetic rescue experiments showed that serotonin is required in adults. Behavioral changes caused by deficient serotonergic signaling were not due to changes in plasma concentrations of sex hormones. We demonstrate that a genetic manipulation reverses sexual preference without involving sex hormones. Our results indicate that serotonin controls sexual preference.<\/jats:p>","DOI":"10.1073\/pnas.1220712110","type":"journal-article","created":{"date-parts":[[2013,5,29]],"date-time":"2013-05-29T01:46:29Z","timestamp":1369791989000},"page":"9968-9973","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":46,"title":["Serotonin signaling in the brain of adult female mice is required for sexual preference"],"prefix":"10.1073","volume":"110","author":[{"given":"Shasha","family":"Zhang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Biomembrane and Membrane Biotechnology and Peking-Tsinghua Center for Life Sciences, School of Life Sciences, and Peking University-International Data Group-McGovern Institute for Brain Research, Peking University, Beijing 100871, China; and"},{"name":"National Institute of Biological Sciences, Beijing 102206, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Biomembrane and Membrane Biotechnology and Peking-Tsinghua Center for Life Sciences, School of Life Sciences, and Peking University-International Data Group-McGovern Institute for Brain Research, Peking University, Beijing 100871, China; 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