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Participants were instructed to associate three neutral shapes with labels for themselves, their best friend, or an unfamiliar other. Functional magnetic resonance imaging data were acquired while participants judged whether the shape-label pairs were maintained or swapped. Behaviorally, participants rapidly tagged a neutral stimulus with self-relevance, showing a robust advantage for self-tagged stimuli. Self-tagging responses were associated with enhanced activity in brain regions linked to self-representation [the ventral medial prefrontal cortex (vmPFC)] and to sensory-driven regions associated with social attention [the left posterior superior temporal sulcus (LpSTS)]. In contrast, associations formed with other people recruited a dorsal frontoparietal control network, with the two networks being inversely correlated. Responses in the vmPFC and LpSTS predicted behavioral self-bias effects. Effective connectivity analyses showed that the vmPFC and the LpSTS were functionally coupled, with the strength of coupling associated with behavioral self-biases. The data show that assignment of personal social significance affects perceptual matching by coupling internal self-representations to brain regions modulating attentional responses to external stimuli.<\/jats:p>","DOI":"10.1073\/pnas.1221862110","type":"journal-article","created":{"date-parts":[[2013,4,23]],"date-time":"2013-04-23T03:10:22Z","timestamp":1366686622000},"page":"7607-7612","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":207,"title":["Coupling social attention to the self forms a network for personal significance"],"prefix":"10.1073","volume":"110","author":[{"given":"Jie","family":"Sui","sequence":"first","affiliation":[{"name":"Department of Experimental Psychology, Oxford University, Oxford OX1 3UD, United Kingdom;"},{"name":"Department of Psychology, and"},{"name":"Department of Biomedical Engineering, Center for Biomedical Imaging Research, School of Medicine, Tsinghua University, Beijing 100084, China; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia","family":"Rotshtein","sequence":"additional","affiliation":[{"name":"School of Psychology, University of Birmingham, Birmingham B15 2TT, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glyn W.","family":"Humphreys","sequence":"additional","affiliation":[{"name":"Department of Experimental Psychology, Oxford University, Oxford OX1 3UD, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2013,4,22]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1086\/261737"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.39.5.773"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/scientificamerican1170-96"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.35.9.677"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.121.3.371"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1037\/a0029792"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2004.01.004"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2005.12.002"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2008.07.010"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1162\/jocn_a_00138"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/35053167"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn907"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1364-6613(99)01417-5"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2006.12.003"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1279.008"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1364-6613(02)00025-6"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-8119(03)00230-1"},{"key":"e_1_3_3_18_2","volume-title":"Handbook of Theory of Mind","author":"Saxe R","year":"2010","unstructured":"R Saxe, The right temporo-parietal junction: A specific brain region for thinking about thoughts. 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