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We provide evidence that this interaction suppresses leukocyte activation and effector functions, implying that species D adenoviruses can affect the host distant from the site of infection.<\/jats:p>","DOI":"10.1073\/pnas.1312420110","type":"journal-article","created":{"date-parts":[[2013,11,11]],"date-time":"2013-11-11T23:48:45Z","timestamp":1384213725000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":57,"title":["A unique secreted adenovirus E3 protein binds to the leukocyte common antigen CD45 and modulates leukocyte functions"],"prefix":"10.1073","volume":"110","author":[{"given":"Mark","family":"Windheim","sequence":"first","affiliation":[{"name":"School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom;"},{"name":"Institute of Biochemistry, Hannover Medical School, 30625 Hannover, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer H.","family":"Southcombe","sequence":"additional","affiliation":[{"name":"School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom;"},{"name":"Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Kremmer","sequence":"additional","affiliation":[{"name":"Institute for Molecular Immunology, Helmholtz Zentrum M\u00fcnchen, German Research Center for Environmental Health, 81377 Munich, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Chaplin","sequence":"additional","affiliation":[{"name":"School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doris","family":"Urlaub","sequence":"additional","affiliation":[{"name":"Department of Immunology, Leibniz Research Centre for Working Environment and Human Factors, 44139 Dortmund, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine S.","family":"Falk","sequence":"additional","affiliation":[{"name":"Institute for Transplantation Immunology, Hannover Medical School, 30625 Hannover, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maren","family":"Claus","sequence":"additional","affiliation":[{"name":"Department of Immunology, Leibniz Research Centre for Working Environment and Human Factors, 44139 Dortmund, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janine","family":"Mihm","sequence":"additional","affiliation":[{"name":"Department of Transplant and Infection Immunology, Saarland University, 66421 Homburg, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myles","family":"Braithwaite","sequence":"additional","affiliation":[{"name":"School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Dennehy","sequence":"additional","affiliation":[{"name":"Institute for Medical Virology, University Hospital T\u00fcbingen, 72076 T\u00fcbingen, Germany; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald","family":"Renz","sequence":"additional","affiliation":[{"name":"Institute for Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps University of Marburg, 35043 Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Sester","sequence":"additional","affiliation":[{"name":"Department of Transplant and Infection Immunology, Saarland University, 66421 Homburg, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten","family":"Watzl","sequence":"additional","affiliation":[{"name":"Department of Immunology, Leibniz Research Centre for Working Environment and Human Factors, 44139 Dortmund, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Gerhard","family":"Burgert","sequence":"additional","affiliation":[{"name":"School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2013,11,11]]},"reference":[{"key":"e_1_3_3_1_2","volume-title":"Virus Taxonomy: Classification and Nomenclature of Viruses. 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