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This structure, along with electron microscopic data on the virus, has provided a three-dimensional picture of the virion. The capsid protein structure has also helped to identify amino acid residues that are required for virus assembly. This information can be used for the development of antiviral therapies that target the viral capsid protein.<\/jats:p>","DOI":"10.1073\/pnas.1316681110","type":"journal-article","created":{"date-parts":[[2013,11,26]],"date-time":"2013-11-26T23:29:43Z","timestamp":1385508583000},"page":"20105-20110","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":42,"title":["Rubella virus capsid protein structure and its role in virus assembly and infection"],"prefix":"10.1073","volume":"110","author":[{"given":"Vidya","family":"Mangala Prasad","sequence":"first","affiliation":[{"name":"Department of Biological Sciences, Purdue University, West Lafayette, IN 47907; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven D.","family":"Willows","sequence":"additional","affiliation":[{"name":"Department of Cell Biology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Fokine","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Purdue University, West Lafayette, IN 47907; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony J.","family":"Battisti","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Purdue University, West Lafayette, IN 47907; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyang","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Purdue University, West Lafayette, IN 47907; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavel","family":"Plevka","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Purdue University, West Lafayette, IN 47907; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom C.","family":"Hobman","sequence":"additional","affiliation":[{"name":"Department of Cell Biology,"},{"name":"Department of Medical Microbiology and Immunology, and"},{"name":"Li KaShing Institute of Virology, University of Alberta, Edmonton, AB, Canada T6G 2H7"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael G.","family":"Rossmann","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Purdue University, West Lafayette, IN 47907; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2013,11,26]]},"reference":[{"key":"e_1_3_4_1_2","first-page":"1069","volume-title":"Fields Virology","author":"Hobman TC","year":"2007","unstructured":"TC Hobman, J Chantler, Rubella virus. 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