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For such interactions, fibronectin serves as a prominent mediator, being translocated from one epithelium (fibronectin-producing) to the other (fibronectin-receiving). This type of interepithelial signaling and the role of fibronectin in these events are conceptually novel and thus open a new way to understand not only how epithelial tissues form in harmony but also how therapeutically to prevent EMT, a critical event in cancer initiation.<\/jats:p>","DOI":"10.1073\/pnas.1316728111","type":"journal-article","created":{"date-parts":[[2014,4,21]],"date-time":"2014-04-21T22:50:54Z","timestamp":1398120654000},"page":"6660-6665","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":21,"title":["Interepithelial signaling with nephric duct is required for the formation of overlying coelomic epithelial cell sheet"],"prefix":"10.1073","volume":"111","author":[{"given":"Takashi","family":"Yoshino","sequence":"first","affiliation":[{"name":"Department of Zoology, Division of Biological Science, Graduate School of Science, Kyoto University, Kitashirakawa, Sakyo-ku, Kyoto 606-8502, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Saito","sequence":"additional","affiliation":[{"name":"Graduate School of Biological Sciences, Nara Institute of Science and Technology, Takayama, Ikoma, Nara 630-0192, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Atsuta","sequence":"additional","affiliation":[{"name":"Department of Zoology, Division of Biological Science, Graduate School of Science, Kyoto University, Kitashirakawa, Sakyo-ku, Kyoto 606-8502, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chihiro","family":"Uchiyama","sequence":"additional","affiliation":[{"name":"Graduate School of Biological Sciences, Nara Institute of Science and Technology, Takayama, Ikoma, Nara 630-0192, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Ueda","sequence":"additional","affiliation":[{"name":"Department of Zoology, Division of Biological Science, Graduate School of Science, Kyoto University, Kitashirakawa, Sakyo-ku, Kyoto 606-8502, Japan;"},{"name":"Graduate School of Biological Sciences, Nara Institute of Science and Technology, Takayama, Ikoma, Nara 630-0192, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyotoshi","family":"Sekiguchi","sequence":"additional","affiliation":[{"name":"Laboratory of Extracellular Matrix Biochemistry, Institute for Protein Research, Osaka University, Yamadaoka, Suita, Osaka 565-0871, Japan; 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