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Furthermore, miR-199a, which is encoded from the opposite strand of\n                    <jats:italic>DNM2<\/jats:italic>\n                    , exerts reciprocal negative regulation upon HIF-1\u03b1 and HIF-2\u03b1. Overexpression of miR-199a decreased HIF-1\u03b1 and HIF-2\u03b1, cell migration, and metastasis. These findings establish a regulatory loop between endocytic pathway and hypoxic response in tumor cells.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1317242111","type":"journal-article","created":{"date-parts":[[2014,3,25]],"date-time":"2014-03-25T01:25:24Z","timestamp":1395710724000},"page":"5331-5336","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":80,"title":["Dynamin 2 along with microRNA-199a reciprocally regulate hypoxia-inducible factors and ovarian cancer metastasis"],"prefix":"10.1073","volume":"111","author":[{"given":"Hemant P.","family":"Joshi","sequence":"first","affiliation":[{"name":"Departments of aPharmacology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indira V.","family":"Subramanian","sequence":"additional","affiliation":[{"name":"Departments of aPharmacology,"},{"name":"Obstetrics and Gynecology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica K.","family":"Schnettler","sequence":"additional","affiliation":[{"name":"Departments of aPharmacology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goutam","family":"Ghosh","sequence":"additional","affiliation":[{"name":"Departments of aPharmacology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesha","family":"Rupaimoole","sequence":"additional","affiliation":[{"name":"Gynecologic Oncology and Reproductive Medicine, Cell Biology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen","family":"Evans","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manju","family":"Saluja","sequence":"additional","affiliation":[{"name":"Departments of aPharmacology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yawu","family":"Jing","sequence":"additional","affiliation":[{"name":"Departments of aPharmacology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Cristina","sequence":"additional","affiliation":[{"name":"Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX 77030; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabita","family":"Roy","sequence":"additional","affiliation":[{"name":"Departments of aPharmacology,"},{"name":"Surgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zeng","sequence":"additional","affiliation":[{"name":"Departments of aPharmacology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay H.","family":"Shah","sequence":"additional","affiliation":[{"name":"Gastroenterology Research Unit, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil K.","family":"Sood","sequence":"additional","affiliation":[{"name":"Gynecologic Oncology and Reproductive Medicine, Cell Biology, and"},{"name":"Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX 77030; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sundaram","family":"Ramakrishnan","sequence":"additional","affiliation":[{"name":"Departments of aPharmacology,"},{"name":"Obstetrics and Gynecology, and"},{"name":"Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2014,3,24]]},"reference":[{"key":"e_1_3_4_1_2","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3322\/canjclin.57.1.43","article-title":"Cancer statistics, 2007","volume":"57","author":"Jemal A","year":"2007","unstructured":"A Jemal, et al., Cancer statistics, 2007. 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