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We previously exploited the strength, directionality, and reversibility of designed metal coordination interactions to arrange a monomeric, redox protein into highly ordered supramolecular architectures. Here we demonstrate that metal-directed self-assembly not only yields very stable architectures but that it also leads to a dramatic stabilization of the individual protein components, whose redox activities can now be utilized for controlled growth of inorganic nanocrystals. These emergent physical and functional properties are attained with minimal modification of the original building blocks.<\/jats:p>","DOI":"10.1073\/pnas.1319866111","type":"journal-article","created":{"date-parts":[[2014,2,11]],"date-time":"2014-02-11T01:09:20Z","timestamp":1392080960000},"page":"2897-2902","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":110,"title":["Exceptionally stable, redox-active supramolecular protein assemblies with emergent properties"],"prefix":"10.1073","volume":"111","author":[{"given":"Jeffrey D.","family":"Brodin","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica R.","family":"Carr","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela A.","family":"Sontz","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. 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