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Confinement to this well-regulated environment may explain how a potentially risky process can occur safely.<\/jats:p>","DOI":"10.1073\/pnas.1321803111","type":"journal-article","created":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T02:13:03Z","timestamp":1396318383000},"page":"5652-5657","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":10,"title":["Receptor revision in CD4 T cells is influenced by follicular helper T cell formation and germinal-center interactions"],"prefix":"10.1073","volume":"111","author":[{"given":"Lauren E.","family":"Higdon","sequence":"first","affiliation":[{"name":"Department of Immunology and"},{"name":"Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, WA 98109"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine A.","family":"Deets","sequence":"additional","affiliation":[{"name":"Department of Immunology and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Travis J.","family":"Friesen","sequence":"additional","affiliation":[{"name":"Department of Immunology and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-Yin","family":"Sze","sequence":"additional","affiliation":[{"name":"Department of Immunology and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela J.","family":"Fink","sequence":"additional","affiliation":[{"name":"Department of Immunology and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2014,3,31]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri1225"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.21.120601.141107"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2567.2010.03250.x"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2006.08.006"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI44752"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.4.2163"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.168.7.3259"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.242321099"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.180.7.4465"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.170.7.3455"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409880102"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/1521-4141(2002010)32:10<2792::AID-IMMU2792>3.0.CO;2-I"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.164.7.3455"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-4141(200005)30:5<1520::AID-IMMU1520>3.0.CO;2-D"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.LAB.0000092228.51605.6A"},{"key":"e_1_3_3_16_2","doi-asserted-by":"crossref","first-page":"3131","DOI":"10.4049\/jimmunol.162.6.3131","article-title":"Chronic modulation of the TCR repertoire in the lymphoid periphery","volume":"162","author":"Blish CA","year":"1999","unstructured":"CA Blish, et al., Chronic modulation of the TCR repertoire in the lymphoid periphery. 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