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An integrative gene mutation analysis in 196 patients with different MDS subtypes allowed a regulatory network of mutually cooperative or exclusive molecules to be discovered among eight functional categories, whereas the combination of a panel of marker genes of prognostic value with the revised-International Prognostic Scoring System may provide a better stratification system for MDS.<\/jats:p>","DOI":"10.1073\/pnas.1407688111","type":"journal-article","created":{"date-parts":[[2014,5,22]],"date-time":"2014-05-22T02:20:02Z","timestamp":1400725202000},"page":"8589-8594","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":54,"title":["Genomic landscape of CD34\n                    <sup>+<\/sup>\n                    hematopoietic cells in myelodysplastic syndrome and gene mutation profiles as prognostic markers"],"prefix":"10.1073","volume":"111","author":[{"given":"Lan","family":"Xu","sequence":"first","affiliation":[{"name":"State 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