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In nonmammalian vertebrates, Ca\n                    <jats:sup>2+<\/jats:sup>\n                    ions entering the mechanosensitive ion channels drive adaptation, but it has been questioned whether this mechanism applies to mammals. We show that adaptation in mammalian cochlear hair cells is, as in other vertebrates, driven by Ca\n                    <jats:sup>2+<\/jats:sup>\n                    entry, demonstrating the importance of this process as a fundamental mechanism in vertebrate hair cells.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1409920111","type":"journal-article","created":{"date-parts":[[2014,9,17]],"date-time":"2014-09-17T00:35:09Z","timestamp":1410914109000},"page":"14918-14923","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":129,"title":["Calcium entry into stereocilia drives adaptation of the mechanoelectrical transducer current of mammalian cochlear hair cells"],"prefix":"10.1073","volume":"111","author":[{"given":"Laura F.","family":"Corns","sequence":"first","affiliation":[{"name":"Department of Biomedical Science, University of Sheffield, Sheffield S10 2TN, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart L.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Biomedical Science, University of Sheffield, Sheffield S10 2TN, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corn\u00e9 J.","family":"Kros","sequence":"additional","affiliation":[{"name":"Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, United Kingdom; and"},{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Groningen, University of Groningen, 9700 RB, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter","family":"Marcotti","sequence":"additional","affiliation":[{"name":"Department of Biomedical Science, University of Sheffield, Sheffield S10 2TN, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2014,9,16]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2295"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1828"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201001138"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5955(89)90176-7"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.cb.08.110192.001353"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.03-05-00962.1983"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.07-09-02821.1987"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.9.3064"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.8.2918"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1989.sp017878"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.17-22-08739.1997"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.1998.159bx.x"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1999.82.5.2171"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.23.1.285"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2159-07.2007"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00038.2013"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn1089"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00136.2009"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.08.025"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1992.0102"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1997.0087"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.04.024"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0803-12.2012"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00893.2002"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1001583"},{"key":"e_1_3_3_26_2","first-page":"440","article-title":"A new probe for cochlear hair bundle stimulation. 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