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The sequences that flank the stalling sites are highly variable but are essential for efficient stalling. Although it has long been assumed that macrolides inhibit translation after the synthesis of a few residues, we found that stalling could occur at any point during translation. Our results reveal a striking conservation of stalling motifs among all known arrest peptides that strongly suggests a universal ribosome stalling mechanism.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1410356111","type":"journal-article","created":{"date-parts":[[2014,10,14]],"date-time":"2014-10-14T00:00:15Z","timestamp":1413244815000},"page":"15379-15384","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":135,"title":["Sequence selectivity of macrolide-induced translational attenuation"],"prefix":"10.1073","volume":"111","author":[{"given":"Amber R.","family":"Davis","sequence":"first","affiliation":[{"name":"Edward A. 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