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Using a memory interference task that pits object (i.e., what) vs. spatial (i.e., where) memories against each other and high-resolution fMRI, we report evidence for two parallel but interacting networks in the human hippocampus and its input regions, supporting prior work in animals. We propose a conceptual model of how object and spatial interference are reduced in the regions providing input to the hippocampus, allowing rich, distinct memories to be built.<\/jats:p>","DOI":"10.1073\/pnas.1411250111","type":"journal-article","created":{"date-parts":[[2014,9,23]],"date-time":"2014-09-23T03:21:36Z","timestamp":1411442496000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":231,"title":["Object and spatial mnemonic interference differentially engage lateral and medial entorhinal cortex in humans"],"prefix":"10.1073","volume":"111","author":[{"given":"Zachariah M.","family":"Reagh","sequence":"first","affiliation":[{"name":"Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697-3800"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Yassa","sequence":"additional","affiliation":[{"name":"Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697-3800"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2014,9,22]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80987-3"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2011.06.006"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.1971.0078"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1037\/0033-295X.102.3.419"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.450040319"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1364-6613(02)02005-3"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20464"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1515\/REVNEURO.2004.15.5.333"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.1077"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1140263"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1135801"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.11.017"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1152882"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1101\/lm.1971111"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4293-12.2013"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1037\/0735-7044.119.2.557"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1080\/02724990444000203"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1037\/0735-7044.118.5.992"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2012.07.035"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2007.08.001"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4978-10.2011"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903500402"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2000.tb06716.x"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature03721"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2011.00069"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20839"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2013.01.036"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1110449"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.22097"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature05601"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3462"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.22224"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3606"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5126-11.2012"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.22223"},{"key":"e_1_3_3_36_2","first-page":"65","article-title":"A simple sequentially rejective multiple test procedure","volume":"6","author":"Holm S","year":"1979","unstructured":"S Holm, A simple sequentially rejective multiple test procedure. 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