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The present study shows that virulence factor expression is controlled by the shift in temperature to 37 \u00b0C, through an RNA thermometer that controls translation of the major virulence regulator protein ToxT. This simple mechanism allows maximal virulence factor expression within the mammalian host and may be more widespread among human pathogens than currently known.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1411570111","type":"journal-article","created":{"date-parts":[[2014,9,17]],"date-time":"2014-09-17T00:35:09Z","timestamp":1410914109000},"page":"14241-14246","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":82,"title":["RNA thermometer controls temperature-dependent virulence factor expression in\n                    <i>Vibrio cholerae<\/i>"],"prefix":"10.1073","volume":"111","author":[{"given":"Gregor G.","family":"Weber","sequence":"first","affiliation":[{"name":"South Texas Center for Emerging Infectious Diseases and Department of Biology, The University of Texas at San Antonio, San Antonio, TX 78249; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Kortmann","sequence":"additional","affiliation":[{"name":"Microbial Biology, Ruhr University Bochum, 44780 Bochum, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz","family":"Narberhaus","sequence":"additional","affiliation":[{"name":"Microbial Biology, Ruhr University Bochum, 44780 Bochum, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl E.","family":"Klose","sequence":"additional","affiliation":[{"name":"South Texas Center for Emerging Infectious Diseases and Department of Biology, The University of Texas at San Antonio, San Antonio, TX 78249; 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