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Through construction and studying of a\n                    <jats:italic>Drosophila<\/jats:italic>\n                    model of neuronal necrosis, we identified a chromatin-modifying cascade to play a key role in execution of neuronal necrosis. Our results indicate that neuronal necrosis is a stereotypically regulated process in both insect and mammalian neurons. This discovery provides previously unidentified biomarkers and potential therapeutic targets for neuronal necrosis.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1413644111","type":"journal-article","created":{"date-parts":[[2014,9,9]],"date-time":"2014-09-09T00:38:33Z","timestamp":1410223113000},"page":"13960-13965","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":35,"title":["Neuronal necrosis is regulated by a conserved chromatin-modifying cascade"],"prefix":"10.1073","volume":"111","author":[{"given":"Kai","family":"Liu","sequence":"first","affiliation":[{"name":"The State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Life Sciences, Peking University, Beijing 100871, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianggong","family":"Ding","sequence":"additional","affiliation":[{"name":"The State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Life 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