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This work opens up a new area for antimalarial research and reinforces the need for structural information in drug design.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1416611112","type":"journal-article","created":{"date-parts":[[2015,1,7]],"date-time":"2015-01-07T06:53:45Z","timestamp":1420613625000},"page":"755-760","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":94,"title":["Antimalarial 4(1H)-pyridones bind to the Q\n                    <sub>i<\/sub>\n                    site of cytochrome\n                    <i>bc<\/i>\n                    <sub>1<\/sub>"],"prefix":"10.1073","volume":"112","author":[{"given":"Michael J.","family":"Capper","sequence":"first","affiliation":[{"name":"Molecular Biophysics Group, Institute of Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool L69 7ZB, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul M.","family":"O\u2019Neill","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science and Engineering, University of Liverpool, Liverpool L69 7ZB, United Kingdom; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Fisher","sequence":"additional","affiliation":[{"name":"Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard W.","family":"Strange","sequence":"additional","affiliation":[{"name":"Molecular Biophysics Group, Institute of Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool L69 7ZB, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren","family":"Moss","sequence":"additional","affiliation":[{"name":"Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen A.","family":"Ward","sequence":"additional","affiliation":[{"name":"Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil G.","family":"Berry","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science and Engineering, University of Liverpool, Liverpool L69 7ZB, United Kingdom; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre S.","family":"Lawrenson","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science and Engineering, University of Liverpool, Liverpool L69 7ZB, United Kingdom; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. 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