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U.S.A."],"published-print":{"date-parts":[[2015,3,3]]},"abstract":"<jats:title>Significance<\/jats:title>\n                  <jats:p>\n                    Many inorganic elements, because they are required for catalysis or as structural components in biomolecules, are essential nutrients for life. In a situation of poor nutrition, organisms economize on the use of these elements by choosing alternate chemistries to achieve the same function. The mechanism of copper economy in\n                    <jats:italic>Chlamydomonas<\/jats:italic>\n                    involves replacement of copper-containing plastocyanin with heme-containing cytochrome (Cyt)\n                    <jats:italic>c<\/jats:italic>\n                    <jats:sub>6<\/jats:sub>\n                    . The copper that is saved by this substitution is used instead for Cyt oxidase biosynthesis. Copper recycling requires proteolysis of plastocyanin dependent on a copper-sensing transcription factor. A candidate protease has been identified.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1422492112","type":"journal-article","created":{"date-parts":[[2015,2,2]],"date-time":"2015-02-02T23:18:45Z","timestamp":1422919125000},"page":"2644-2651","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":94,"title":["Copper economy in\n                    <i>Chlamydomonas<\/i>\n                    : Prioritized allocation and reallocation of copper to respiration vs. photosynthesis"],"prefix":"10.1073","volume":"112","author":[{"given":"Janette","family":"Kropat","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean D.","family":"Gallaher","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugen I.","family":"Urzica","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacie S.","family":"Nakamoto","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Strenkert","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Tottey","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew Z.","family":"Mason","sequence":"additional","affiliation":[{"name":"Institute for Integrated Research in Materials, Environments, and Societies, California State University, Long Beach, CA 90840"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabeeha S.","family":"Merchant","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, and"},{"name":"Institute for Genomics and Proteomics, University of California, Los Angeles, CA 90095; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2015,2,2]]},"reference":[{"key":"e_1_3_3_1_2","volume-title":"Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life\u2014An Introduction and Guide","author":"Kaim W","year":"1994","unstructured":"W Kaim, B Schwederski Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life\u2014An Introduction and Guide (Wiley, Chichester, UK, 1994)."},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1016710810701"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0303-2647(83)90029-1"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00775-008-0404-5"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.nu.08.070188.001315"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03450110087033"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/51.2.225"},{"key":"e_1_3_3_8_2","first-page":"261","article-title":"Zinc and copper in the tissues and serum of cadmium intoxicated guinea-pigs: Influence of vitamin C","volume":"42","author":"Kadrabov\u00e1 J","year":"1993","unstructured":"J Kadrabov\u00e1, A Madaric, E Ginter, Zinc and copper in the tissues and serum of cadmium intoxicated guinea-pigs: Influence of vitamin C. 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