{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T14:15:31Z","timestamp":1791036931307,"version":"4.1.0"},"reference-count":45,"publisher":"National Academy of Sciences","issue":"15","content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[2000,7,18]]},"abstract":"<jats:p>\n                    Mutation of the reeler gene (\n                    <jats:italic>Reln<\/jats:italic>\n                    ) disrupts neuronal migration in several brain regions and gives rise to functional deficits such as ataxic gait and trembling in the reeler mutant mouse. Thus, the\n                    <jats:italic>Reln<\/jats:italic>\n                    product, reelin, is thought to control cell\u2013cell interactions critical for cell positioning in the brain. Although an abundance of reelin transcript is found in the embryonic spinal cord [Ikeda, Y. &amp; Terashima, T. (1997)\n                    <jats:italic>Dev. Dyn.<\/jats:italic>\n                    210, 157\u2013172; Schiffmann, S. N., Bernier, B. &amp; Goffinet, A. M. (1997)\n                    <jats:italic>Eur. J. Neurosci.<\/jats:italic>\n                    9, 1055\u20131071], it is generally thought that neuronal migration in the spinal cord is not affected by reelin. Here, however, we show that migration of sympathetic preganglionic neurons in the spinal cord is affected by reelin. This study thus indicates that reelin affects neuronal migration outside of the brain. Moreover, the relationship between reelin and migrating preganglionic neurons suggests that reelin acts as a barrier to neuronal migration.\n                  <\/jats:p>","DOI":"10.1073\/pnas.150040497","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T10:41:48Z","timestamp":1027680108000},"page":"8612-8616","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":97,"title":["Reelin controls position of autonomic neurons in the spinal cord"],"prefix":"10.1073","volume":"97","author":[{"given":"Joseph W.","family":"Yip","sequence":"first","affiliation":[{"name":"Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261; Department of Molecular Neurobiology, Institute of DNA Medicine, Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan; and Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and 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