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Additionally, influenza strains have demonstrated the ability to develop resistance to existing antivirals, including oseltamivir. As such, there is a need for novel interventions that can treat and\/or prevent serious influenza infection. We demonstrate that VIS410, a human mAb, neutralizes a wide range of influenza A viruses and effectively manages H7N9 infection.<\/jats:p>","DOI":"10.1073\/pnas.1502374112","type":"journal-article","created":{"date-parts":[[2015,8,17]],"date-time":"2015-08-17T22:41:06Z","timestamp":1439851266000},"page":"10890-10895","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":81,"title":["A broadly neutralizing human monoclonal antibody is effective against H7N9"],"prefix":"10.1073","volume":"112","author":[{"given":"Kannan","family":"Tharakaraman","sequence":"first","affiliation":[{"name":"Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vidya","family":"Subramanian","sequence":"additional","affiliation":[{"name":"Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karthik","family":"Viswanathan","sequence":"additional","affiliation":[{"name":"Visterra, Inc., Cambridge, MA 02139;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Sloan","sequence":"additional","affiliation":[{"name":"Visterra, Inc., Cambridge, MA 02139;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Ling","family":"Yen","sequence":"additional","affiliation":[{"name":"School of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region of China, Pokfulam, Hong Kong;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dale L.","family":"Barnard","sequence":"additional","affiliation":[{"name":"Institute of Antiviral Research, Utah State University, Logan, UT 84322"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. 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