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Computational modeling suggests this spatial mismatch has critical functional consequences on neuronal output, allowing the cell to downregulate its own excitability and thus respond homeostatically to chronic stimulation.<\/jats:p>","DOI":"10.1073\/pnas.1502902112","type":"journal-article","created":{"date-parts":[[2015,7,20]],"date-time":"2015-07-20T20:23:40Z","timestamp":1437423820000},"page":"9757-9762","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":120,"title":["Activity-dependent mismatch between axo-axonic synapses and the axon initial segment controls neuronal output"],"prefix":"10.1073","volume":"112","author":[{"given":"Winnie","family":"Wefelmeyer","sequence":"first","affiliation":[{"name":"MRC Centre for Developmental Neurobiology, King\u2019s College London, London SE1 1UL, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Cattaert","sequence":"additional","affiliation":[{"name":"Institut de Neurosciences Cognitives et Int\u00e9gratives d'Aquitaine, Universit\u00e9 de Bordeaux, CNRS, 33076 Bordeaux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Burrone","sequence":"additional","affiliation":[{"name":"MRC Centre for Developmental Neurobiology, King\u2019s College London, London SE1 1UL, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2015,7,20]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00048.2009"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-neuro-062111-150339"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2014.03.004"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4064-11.2011"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2010.04.012"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2014.01.009"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(82)90086-0"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(83)91076-4"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1227622"},{"key":"e_1_3_3_10_2","article-title":"Dentate gyrus local circuit is implicated in learning under stress\u2014A role for neurofascin","author":"Zitman FM","year":"2014","unstructured":"FM Zitman, , Dentate gyrus local circuit is implicated in learning under stress\u2014A role for neurofascin. 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