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This result was accompanied by significantly reduced inflammation, oxidative stress, and fibrotic deposition in old, degenerated\n                    <jats:italic>mdx<\/jats:italic>\n                    muscle. These findings indicate that simvastatin is a promising, novel therapeutic approach for DMD and related muscle disorders.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1509536112","type":"journal-article","created":{"date-parts":[[2015,9,28]],"date-time":"2015-09-28T22:53:45Z","timestamp":1443480825000},"page":"12864-12869","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":96,"title":["A new therapeutic effect of simvastatin revealed by functional improvement in muscular dystrophy"],"prefix":"10.1073","volume":"112","author":[{"given":"Nicholas P.","family":"Whitehead","sequence":"first","affiliation":[{"name":"Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Jeong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth L.","family":"Bible","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marvin E.","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley C.","family":"Froehner","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2015,9,28]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1517\/14728214.2012.691965"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3008873"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/NEN.0b013e3181aa31c2"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.4054"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0015354"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1160\/TH12-05-0337"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.112.300922"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2014.03.019"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40272-014-0116-y"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-008-9364-3"},{"key":"e_1_3_3_11_2","first-page":"47","article-title":"Muscular effects of statins in the elderly female: A review","volume":"8","author":"Bhardwaj S","year":"2013","unstructured":"S Bhardwaj, S Selvarajah, EB Schneider, Muscular effects of statins in the elderly female: A review. 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