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Its application to formamide, a centerpiece of prebiotic chemistry, unveils very different reaction networks between gas and solution regimes, indicating, in the liquid phase, new pathways, intermediates, and products. The new scheme allows us also to demonstrate the comparable relative stability of formamide, hydrogen cyanide, and formic acid, thus contributing insight to a heated current debate in the prebiotic chemistry community.<\/jats:p>","DOI":"10.1073\/pnas.1512486112","type":"journal-article","created":{"date-parts":[[2015,11,23]],"date-time":"2015-11-23T22:19:00Z","timestamp":1448317140000},"page":"15030-15035","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":141,"title":["Formamide reaction network in gas phase and solution via a unified theoretical approach: Toward a reconciliation of different prebiotic scenarios"],"prefix":"10.1073","volume":"112","author":[{"given":"Fabio","family":"Pietrucci","sequence":"first","affiliation":[{"name":"Institut de Min\u00e9ralogie, de Physique des Mat\u00e9riaux et de Cosmochimie, Universit\u00e9 Pierre et Marie Curie, Sorbonne Universit\u00e9s, CNRS, Mus\u00e9um National d\u2019Histoire Naturelle, Institut de Recherche pour le D\u00e9veloppement, UMR 7590, F-75005 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonino Marco","family":"Saitta","sequence":"additional","affiliation":[{"name":"Institut de Min\u00e9ralogie, de Physique des Mat\u00e9riaux et de Cosmochimie, Universit\u00e9 Pierre et Marie Curie, Sorbonne Universit\u00e9s, CNRS, Mus\u00e9um National d\u2019Histoire Naturelle, Institut de Recherche pour le D\u00e9veloppement, UMR 7590, F-75005 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2015,11,23]]},"reference":[{"key":"e_1_3_3_1_2","first-page":"188","article-title":"Letter to Joseph Hooker [7471]","volume":"19","author":"Darwin CD","year":"1871","unstructured":"CD Darwin, Letter to Joseph Hooker [7471]. 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