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Direct sensing of \u03b2-lactam antibiotics may enable sufficiently rapid induction of \u03b2-lactamase to degrade \u03b2-lactam antibiotics before the integrity of the cell wall is disturbed.<\/jats:p>","DOI":"10.1073\/pnas.1520300113","type":"journal-article","created":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T23:45:31Z","timestamp":1454370331000},"page":"1648-1653","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":80,"title":["Sensor histidine kinase is a \u03b2-lactam receptor and induces resistance to \u03b2-lactam antibiotics"],"prefix":"10.1073","volume":"113","author":[{"given":"Lu","family":"Li","sequence":"first","affiliation":[{"name":"Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT 06269-3089;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiyao","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioreactor 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