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We used this initial insight to show that such elements are highly conserved, and that through predictive modeling, we can gain global insight into key determinants of GATA1 transcriptional activity.<\/jats:p>","DOI":"10.1073\/pnas.1521754113","type":"journal-article","created":{"date-parts":[[2016,4,4]],"date-time":"2016-04-04T23:51:28Z","timestamp":1459813888000},"page":"4434-4439","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":68,"title":["Insight into GATA1 transcriptional activity through interrogation of\n                    <i>cis<\/i>\n                    elements disrupted in human erythroid disorders"],"prefix":"10.1073","volume":"113","author":[{"given":"Aoi","family":"Wakabayashi","sequence":"first","affiliation":[{"name":"Division of Hematology\/Oncology, Manton Center for Orphan Disease Research, Boston Children\u2019s Hospital, Boston, MA 02115;"},{"name":"Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA; 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