{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T18:50:07Z","timestamp":1793299807215,"version":"4.5.0"},"reference-count":74,"publisher":"National Academy of Sciences","issue":"15","content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[2016,4,12]]},"abstract":"<jats:title>Significance<\/jats:title>\n                  <jats:p>\n                    Interest in male mosquitoes has been motivated by the potential to develop novel vector control strategies, exploiting the fact that males do not feed on blood or transmit diseases, such as malaria. However, genetic studies of male\n                    <jats:italic>Anopheles<\/jats:italic>\n                    mosquitoes have been impeded by the lack of molecular characterization of the Y chromosome. Here we show that the\n                    <jats:italic>Anopheles gambiae<\/jats:italic>\n                    Y chromosome contains a very small repertoire of genes, with massively amplified tandem arrays of a small number of satellites and transposable elements constituting the vast majority of the sequence. These genes and repeats evolve rapidly, bringing about remodeling of the Y, even among closely related species. Our study provides a long-awaited foundation for studying mosquito Y chromosome biology and evolution.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1525164113","type":"journal-article","created":{"date-parts":[[2016,3,29]],"date-time":"2016-03-29T22:14:13Z","timestamp":1459289653000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":101,"title":["Radical remodeling of the Y chromosome in a recent radiation of malaria mosquitoes"],"prefix":"10.1073","volume":"113","author":[{"given":"Andrew Brantley","family":"Hall","sequence":"first","affiliation":[{"name":"The Interdisciplinary PhD Program in Genetics, Bioinformatics, and Computational Biology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippos-Aris","family":"Papathanos","sequence":"additional","affiliation":[{"name":"Section of Genomics and Genetics, Department of 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24061;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolai","family":"Windbichler","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simo","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Informatics and Computing, Indiana University, Bloomington, IN 47405;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5731-8808","authenticated-orcid":false,"given":"Matthew W.","family":"Hahn","sequence":"additional","affiliation":[{"name":"School of Informatics and Computing, Indiana University, Bloomington, IN 47405;"},{"name":"Department of Biology, Indiana University, Bloomington, IN 47405;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2983-8934","authenticated-orcid":false,"given":"Adam 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