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Here we demonstrate a critical role for two highly related cytokines, IL-2 and IL-15, in the terminal differentiation of highly exhausted CD8\n                    <jats:sup>+<\/jats:sup>\n                    T cells and the lack of immunological memory observed during chronic viral infection.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1604256113","type":"journal-article","created":{"date-parts":[[2016,8,29]],"date-time":"2016-08-29T22:33:17Z","timestamp":1472509997000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":71,"title":["IL2R\u03b2-dependent signals drive terminal exhaustion and suppress memory development during chronic viral infection"],"prefix":"10.1073","volume":"113","author":[{"given":"Jean-Christophe","family":"Beltra","sequence":"first","affiliation":[{"name":"Cytokines and Adaptive Immunity Laboratory, Sainte-Justine University Hospital Research Center, Montreal, QC, Canada H3T 1C5;"},{"name":"Department 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