{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T14:53:16Z","timestamp":1781103196531,"version":"3.54.1"},"reference-count":71,"publisher":"National Academy of Sciences","issue":"47","license":[{"start":{"date-parts":[[2017,5,7]],"date-time":"2017-05-07T00:00:00Z","timestamp":1494115200000},"content-version":"vor","delay-in-days":181,"URL":"http:\/\/www.pnas.org\/site\/misc\/userlicense.xhtml"}],"funder":[{"DOI":"10.13039\/100000053","name":"HHS | NIH | National Eye Institute","doi-asserted-by":"publisher","award":["R01-EY024067"],"award-info":[{"award-number":["R01-EY024067"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000185","name":"DOD | Defense Advanced Research Projects Agency","doi-asserted-by":"publisher","award":["W911NF-14-2-0043"],"award-info":[{"award-number":["W911NF-14-2-0043"]}],"id":[{"id":"10.13039\/100000185","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000893","name":"Simons Foundation","doi-asserted-by":"publisher","award":["325548"],"award-info":[{"award-number":["325548"]}],"id":[{"id":"10.13039\/100000893","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.pnas.org"],"crossmark-restriction":true},"short-container-title":["Proc. Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[2016,11,22]]},"abstract":"<jats:title>Significance<\/jats:title>\n                  <jats:p>A central question in systems neuroscience is how cognitive functions can arise from the interplay of many different brain areas. For example the cognitive act of forming a decision requires a concerted computation involving sensory, mnemonic, and executive information residing in neural circuits that have different anatomical locations, that operate on different temporal scales, and that extend over different spatial dimensions. We find that in a central cortical hub\u2014the posterior parietal cortex\u2014firing rate information about upcoming decisions is pulsed according to intrinsic temporal structure in the beta- and gamma-frequency ranges. The brain may use temporal structure at several time scales to support distributed computations that underlie reward-guided decisions.<\/jats:p>","DOI":"10.1073\/pnas.1606479113","type":"journal-article","created":{"date-parts":[[2016,11,7]],"date-time":"2016-11-07T22:55:04Z","timestamp":1478559304000},"page":"13492-13497","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":40,"title":["Temporal coding of reward-guided choice in the posterior parietal cortex"],"prefix":"10.1073","volume":"113","author":[{"given":"David J.","family":"Hawellek","sequence":"first","affiliation":[{"name":"Center for Neural Science, New York University, New York, NY 10003;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan T.","family":"Wong","sequence":"additional","affiliation":[{"name":"Center for Neural Science, New York University, New York, NY 10003;"},{"name":"Department of Electrical and Electronic Engineering, The University of Melbourne, Melbourne, 3010 VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bijan","family":"Pesaran","sequence":"additional","affiliation":[{"name":"Center for Neural Science, New York University, New York, NY 10003;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2016,11,7]]},"reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/386167a0"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.285.5425.257"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.2001.86.4.1916"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4684-04.2005"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2007.09.031"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.29.051605.113038"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4274-06.2007"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-neuro-060909-152823"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.12.035"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00867.2011"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2451-14.2015"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaa4056"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4210"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/22268"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2004.09.009"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1094765"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1479-09.2009"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5742-09.2010"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1169405"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1115270"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature06849"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2009.09.003"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.051508.135409"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aab0551"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature18617"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2010.04.004"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/0959-4388(95)80012-3"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1099745"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/35094565"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2005.08.011"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2015.09.034"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1038\/35086012"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1038\/35067550"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphysparis.2007.01.005"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.450030307"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1128115"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.81.3291"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4250-04.2005"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4122-11.2012"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1162\/neco.1995.7.3.469"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature00807"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(03)00120-X"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2004.12.025"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2008.02.023"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2009.01.008"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1002717"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0908193106"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1114223109"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2011.03.007"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.12.027"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1402773111"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.12.018"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3668"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00263.2005"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2010.09.001"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.15-01-00047.1995"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2008.09.014"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.03.007"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2007.05.005"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00035.2008"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(96)80019-1"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(02)01186-8"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1124593"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.3389\/neuro.06.006.2009"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2015.07.026"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(99)77236-X"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1162\/089976601300014312"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.1058"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1625-13.2013"},{"key":"e_1_3_3_70_2","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: A practical and powerful approach to multiple testing","volume":"57","author":"Benjamini Y","year":"1995","unstructured":"Y Benjamini, Y Hochberg, Controlling the false discovery rate: A practical and powerful approach to multiple testing. J R Stat Soc B 57, 289\u2013300 (1995).","journal-title":"J R Stat Soc B"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00853.2003"}],"container-title":["Proceedings of the National Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.pnas.org\/syndication\/doi\/10.1073\/pnas.1606479113","content-type":"unspecified","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pnas.org\/doi\/pdf\/10.1073\/pnas.1606479113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T08:10:27Z","timestamp":1718871027000},"score":1,"resource":{"primary":{"URL":"https:\/\/pnas.org\/doi\/full\/10.1073\/pnas.1606479113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,7]]},"references-count":71,"journal-issue":{"issue":"47","published-print":{"date-parts":[[2016,11,22]]}},"alternative-id":["10.1073\/pnas.1606479113"],"URL":"https:\/\/doi.org\/10.1073\/pnas.1606479113","relation":{},"ISSN":["0027-8424","1091-6490"],"issn-type":[{"value":"0027-8424","type":"print"},{"value":"1091-6490","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,7]]},"assertion":[{"value":"2016-11-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}