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Natl. Acad. Sci. U.S.A."],"published-print":{"date-parts":[[2016,8,2]]},"abstract":"<jats:title>Significance<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Legionella<\/jats:italic>\n                    <jats:italic>pneumophila<\/jats:italic>\n                    , the bacterium causing Legionnaires\u2019 disease, invades lung cells by creating intracellular vacuoles where it is protected and where it can multiply. For expansion, the vacuoles must hijack intracellular vesicles while avoiding destruction by lysosomes. To achieve these goals,\n                    <jats:italic>Legionella<\/jats:italic>\n                    exports effector proteins into the cytoplasm and into the membrane of the vacuole. Here we report that certain\n                    <jats:italic>Legionella<\/jats:italic>\n                    effectors mimic intracellular fusion proteins of the SNARE family, allowing them to selectively fuse with specific intracellular transport vesicles, thus providing more space for the dividing bacteria. In contrast to SNAREs, however, the\n                    <jats:italic>Legionella<\/jats:italic>\n                    proteins can be used only once, thus allowing the bacteria to control the amount of hijacked vesicles.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1608755113","type":"journal-article","created":{"date-parts":[[2016,7,19]],"date-time":"2016-07-19T22:55:22Z","timestamp":1468968922000},"page":"8807-8812","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":46,"title":["Direct targeting of membrane fusion by SNARE mimicry: Convergent evolution of\n                    <i>Legionella<\/i>\n                    effectors"],"prefix":"10.1073","volume":"113","author":[{"given":"Xingqi","family":"Shi","sequence":"first","affiliation":[{"name":"Department of Microbiology, University of Chicago, Chicago, IL 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