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U.S.A."],"published-print":{"date-parts":[[2017,5,30]]},"abstract":"<jats:title>Significance<\/jats:title>\n                  <jats:p>Mathematical and computational modeling approaches can be essential in providing quantitative scenarios of disease spreading, as well as projecting the impact in the population. Here we analyze the spatial and temporal dynamics of the Zika virus epidemic in the Americas with a microsimulation approach informed by high-definition demographic, mobility, and epidemic data. The model provides probability distributions for the time and place of introduction of Zika in Brazil, the estimate of the attack rate, timing of the epidemic in the affected countries, and the projected number of newborns from women infected by Zika. These results are potentially relevant in the preparation and analysis of contingency plans aimed at Zika virus control.<\/jats:p>","DOI":"10.1073\/pnas.1620161114","type":"journal-article","created":{"date-parts":[[2017,4,25]],"date-time":"2017-04-25T20:40:13Z","timestamp":1493152813000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":241,"title":["Spread of Zika virus in the Americas"],"prefix":"10.1073","volume":"114","author":[{"given":"Qian","family":"Zhang","sequence":"first","affiliation":[{"name":"Laboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA 02115;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaiyuan","family":"Sun","sequence":"additional","affiliation":[{"name":"Laboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA 02115;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Chinazzi","sequence":"additional","affiliation":[{"name":"Laboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA 02115;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Pastore y Piontti","sequence":"additional","affiliation":[{"name":"Laboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA 02115;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie E.","family":"Dean","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, College of Public Health and Health Professions, University of Florida, Gainesville, FL 32611;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana Patricia","family":"Rojas","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, College of Public Health and Health Professions, University of Florida, Gainesville, FL 32611;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Merler","sequence":"additional","affiliation":[{"name":"Bruno Kessler Foundation, 38123 Trento, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina","family":"Mistry","sequence":"additional","affiliation":[{"name":"Laboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA 02115;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piero","family":"Poletti","sequence":"additional","affiliation":[{"name":"Dondena Centre for Research on Social Dynamics and Public Policy, Universit\u00e1 Commerciale L. 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