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Additionally, these glycoside hydrolases can be used to potentiate antifungal drugs by increasing their hyphal penetration, to protect human cells from fungal-induced injury, and attenuate virulence of\n                    <jats:italic>A. fumigatus<\/jats:italic>\n                    in a mouse model of invasive aspergillosis. The findings of this study identify recombinant microbial glycoside hydrolases as promising therapeutics with the potential for antibiofilm activity against pathogens across different taxonomic kingdoms.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1702798114","type":"journal-article","created":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T20:40:29Z","timestamp":1497991229000},"page":"7124-7129","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":95,"title":["Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity"],"prefix":"10.1073","volume":"114","author":[{"given":"Brendan D.","family":"Snarr","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology, McGill University, Montreal, QC, H3A 2B4, Canada;"},{"name":"Department of Medicine, Infectious Diseases and Immunity in Global Health Program, Centre for Translational Biology, McGill University Health Centre, 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