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Our work provides insights into how biochemistry is remodeled in these two disorders, revealing candidate biomarkers that may prove to have clinical utility.<\/jats:p>","DOI":"10.1073\/pnas.1703338114","type":"journal-article","created":{"date-parts":[[2017,7,17]],"date-time":"2017-07-17T21:00:34Z","timestamp":1500325234000},"page":"8402-8407","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":41,"title":["Metabolic profiles of exercise in patients with McArdle disease or mitochondrial myopathy"],"prefix":"10.1073","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9524-2691","authenticated-orcid":false,"given":"Nigel F.","family":"Delaney","sequence":"first","affiliation":[{"name":"Howard Hughes Medical Institute, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114;"},{"name":"Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114;"},{"name":"The Broad Institute, Cambridge, MA 02142;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Sharma","sequence":"additional","affiliation":[{"name":"Howard Hughes Medical Institute, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114;"},{"name":"Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114;"},{"name":"The Broad Institute, Cambridge, MA 02142;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Tadvalkar","sequence":"additional","affiliation":[{"name":"Howard Hughes Medical Institute, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114;"},{"name":"Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114;"},{"name":"The Broad Institute, Cambridge, MA 02142;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clary B.","family":"Clish","sequence":"additional","affiliation":[{"name":"The Broad Institute, Cambridge, MA 02142;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald G.","family":"Haller","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX 75390;"},{"name":"Veterans Affairs Medical Center, Institute for Exercise and Environmental Medicine of Texas Health Presbyterian Hospital, Dallas, TX 75231"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vamsi K.","family":"Mootha","sequence":"additional","affiliation":[{"name":"Howard Hughes Medical Institute, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114;"},{"name":"Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114;"},{"name":"The Broad Institute, Cambridge, MA 02142;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"341","published-online":{"date-parts":[[2017,7,17]]},"reference":[{"key":"e_1_3_3_1_2","unstructured":"Y-T Chen PS Kishnani D Koeberl Glycogen storage diseases. 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