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The significance of this work includes: (\n                    <jats:italic>i<\/jats:italic>\n                    ) a modular synthetic strategy for the preparation of ciprofloxacin derivatives in high yields in one step at room temperature without any catalysts; (\n                    <jats:italic>ii<\/jats:italic>\n                    ) stable nanoaggregates, prepared following the principle of aggregation-induced emission, and successfully used as fluorescent organic dots to image bacteria; and (\n                    <jats:italic>iii<\/jats:italic>\n                    ) formulation of nanodrugs that showed aggregation-enhanced antibacterial activities.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1708556114","type":"journal-article","created":{"date-parts":[[2017,7,25]],"date-time":"2017-07-25T20:40:22Z","timestamp":1501015222000},"page":"8464-8469","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":86,"title":["Design and synthesis of theranostic antibiotic nanodrugs that display enhanced antibacterial activity and luminescence"],"prefix":"10.1073","volume":"114","author":[{"given":"Sheng","family":"Xie","sequence":"first","affiliation":[{"name":"Department of Chemistry, KTH Royal Institute of Technology, Teknikringen 30, S-10044, Stockholm, Sweden;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sesha","family":"Manuguri","sequence":"additional","affiliation":[{"name":"Department of Chemistry, KTH Royal Institute of Technology, Teknikringen 30, S-10044, Stockholm, Sweden;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giampiero","family":"Proietti","sequence":"additional","affiliation":[{"name":"Department of Chemistry, KTH Royal Institute of Technology, Teknikringen 30, S-10044, Stockholm, Sweden;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joakim","family":"Romson","sequence":"additional","affiliation":[{"name":"Department of Chemistry, KTH Royal Institute of Technology, Teknikringen 30, S-10044, Stockholm, Sweden;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Applied Physics, Science for Life Laboratory, KTH Royal Institute of Technology, SE-171 21, Solna, Sweden;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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