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Notably, administering a nematode-derived steroid, \u03947-dafachronic acid, which acts through a receptor within\n                    <jats:italic>S. stercoralis<\/jats:italic>\n                    to regulate parasite development, significantly diminished autoinfection in glucocorticoid-treated NSG mice. This opens the possibility of new chemotherapy for hyperinfective strongyloidiasis, targeting the parasite\u2019s own steroid hormone mechanisms.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1712235114","type":"journal-article","created":{"date-parts":[[2017,12,4]],"date-time":"2017-12-04T14:56:48Z","timestamp":1512399408000},"page":"204-209","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":50,"title":["Methylprednisolone acetate induces, and \u03947-dafachronic acid suppresses,\n                    <i>Strongyloides stercoralis<\/i>\n                    hyperinfection in NSG mice"],"prefix":"10.1073","volume":"115","author":[{"given":"John B.","family":"Patton","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA 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