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Thin filament length is closely associated with specific contractile properties of individual muscles, and it is tightly controlled by actin binding proteins. However, it is still unclear how these proteins work in concert to maintain proper thin filament length and whether there are additional factors involved. In this study, we found that deleting HSPB7 resulted in uncontrolled elongation of actin filaments and the formation of atypical actin filament bundles in cardiomyocytes. 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