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Our work provides a solid new foundation for therapeutic development of FD and understanding the principles whereby G\u03b1\n                    <jats:sub>s<\/jats:sub>\n                    signaling governs bone formation and maintenance and bone marrow stromal cell differentiation.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1714313114","type":"journal-article","created":{"date-parts":[[2018,1,16]],"date-time":"2018-01-16T13:05:29Z","timestamp":1516107929000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":67,"title":["Induced\n                    <i>Gnas<\/i>\n                    <sup>\n                      <i>R201H<\/i>\n                    <\/sup>\n                    expression from the endogenous\n                    <i>Gnas<\/i>\n                    locus causes fibrous dysplasia by up-regulating Wnt\/\u03b2-catenin signaling"],"prefix":"10.1073","volume":"115","author":[{"given":"Sanjoy Kumar","family":"Khan","sequence":"first","affiliation":[{"name":"Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prem Swaroop","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gene","family":"Elliott","sequence":"additional","affiliation":[{"name":"National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorothy Zhang","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, MA 02115;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoshi","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115;"},{"name":"West China School of Stomatology, Sichuan University, Chengdu 610041, P. 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