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U.S.A."],"published-print":{"date-parts":[[2018,5,22]]},"abstract":"<jats:title>Significance<\/jats:title>\n                  <jats:p>\n                    We show that mutations in\n                    <jats:italic>HMGA2<\/jats:italic>\n                    affect fetal resource allocation, testis descent, and the size of pigs and provides a target for gene modification that can be used to modulate size in other mammalian species. This can have implications in agriculture as well as in the development of new strains of companion animals. In addition, most xenograft pig donors have adult organs larger than those of humans. Recently, it has been shown that regulation of organ growth is donor-controlled, not host-controlled, resulting in organ overgrowth and damage after transplantation. 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