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We previously reported that lower vertebrate pineal organs, which discriminate between UV and visible light, employ a bistable opsin called parapinopsin that has two stable photointerconvertible states, a signaling-inactive state maximally sensitive to UV and a visible light-sensitive signaling-active photoproduct. Here, we present evidence that the photoequilibrium between these two states in the zebrafish pineal organ is dependent on the spectral composition of incident light, setting the opsin\u2019s signaling activity according to color to allow parapinopsin alone to generate color opponency between UV and visible light at the level of single pineal photoreceptor cells.<\/jats:p>","DOI":"10.1073\/pnas.1802592115","type":"journal-article","created":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T15:15:14Z","timestamp":1539616514000},"page":"11310-11315","update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":36,"title":["Color opponency with a single kind of bistable opsin in the zebrafish pineal organ"],"prefix":"10.1073","volume":"115","author":[{"given":"Seiji","family":"Wada","sequence":"first","affiliation":[{"name":"Department of Biology and Geosciences, Graduate School of Science, Osaka City University, 558-8585 Osaka, 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