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The activity of YRS\n                    <jats:sup>ACT<\/jats:sup>\n                    is independent of thrombopoietin (TPO), as evidenced by expansion of the megakaryocytes from iPS cell-derived hematopoietic stem cells from a patient deficient in TPO signaling. These findings demonstrate a previously unrecognized function of an aaRS which may have implications for therapeutic interventions.\n                  <\/jats:p>","DOI":"10.1073\/pnas.1807000115","type":"journal-article","created":{"date-parts":[[2018,8,13]],"date-time":"2018-08-13T15:10:32Z","timestamp":1534173032000},"update-policy":"https:\/\/doi.org\/10.1073\/pnas.cm10313","source":"Crossref","is-referenced-by-count":47,"title":["Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia"],"prefix":"10.1073","volume":"115","author":[{"given":"Taisuke","family":"Kanaji","sequence":"first","affiliation":[{"name":"Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037;"},{"name":"MERU-Roon Research Center on Vascular Biology and Thrombosis, The Scripps Research Institute, La Jolla, CA 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